Adhesives, coated with microscopic needles 250 microns wide and 650 microns long, can introduce a DNA vaccine into the body. Such vaccines can help develop immunity against several diseases.
The meaning of such vaccines is to familiarize the body with the genes of pathogens. The cells produce molecules grafted human pathogen, which signals the immune system of the aliens. DNA vaccines are more beneficial than usual.
For example, do not need to spend time on the production and purification of proteins from pathogens. In theory, all make the body itself. Scientists have tried many times to increase the efficiency of DNA vaccines, for example, referring to electricity.
Now they have decided to cover the microneedle biodegradable film containing vaccines and other molecules (compounds that stimulate the immune system and help cells take DNA). The needles do not damage the nerves and blood vessels, which relieves pain and possible complications.
The film remains in the body even after removal of the patch, says researcher Peter Demat. It is dissolved in a certain way. Terms can vary from a few days to weeks. Prolonged effect of the vaccine means developing effective immune protection.
Patches tested in rhesus monkeys. The animals were measured protein levels associated with the DNA vaccine. It turned out macaque worked out 140 times more protein in response to the microneedles compared to conventional vaccination. Also, importantly, the patches can be stored at room temperature for several weeks.